Papillomatosis

Compartment: Epidermis

Alt text: "Two-panel histologic comparison of papillomatosis. Panel A shows fine papillomatosis with slender epidermal projections containing koilocytes, vertical parakeratosis, and thrombosed capillaries within fibrovascular cores, as in verruca vulgaris. Panel B shows coarse papillomatosis with broad, irregular epidermal projections, horn cysts, hyperkeratosis, and acanthosis, as in seborrheic keratosis."
Caption: “Papillomatosis: fine (A, verruca vulgaris) versus coarse (B, seborrheic keratosis) upward epidermal projections.”

Definition: Upward, finger-like projections of the epidermis supported by cores of fibrovascular tissue.

Clinical Context: Verruca vulgaris, Inverted follicular keratosis, Hyperkeratotic seborrheic keratosis

Key Feature: Undulating, serrated, or spired epidermal contour.

🔗 Related Terms: Acanthosis, Hyperkeratosis, Pseudoepitheliomatous hyperplasia